WHY CALCIUM-D-GLUCARATE?

A SUPPLEMENT TO SUPPPORT DETOXIFICATION

YOUR BODY IS AMAZING

Your body is amazing! It is always working behind the scenes to support you. 

Do you remember Benjamin Franklin’s old saying: “An ounce of prevention is worth a pound of cure?” Your prevention is supporting your body with self care, sleep, being in nature, exercise and of course organic, unrefined, unprocessed foods, as fresh as possible and in their natural state. This is the best way to prevent overburdening your body with unwanted toxins.

Toxins will still find a way into your body: through the air you breathe, water you drink, foods you eat, items you clean with and products you put on your skin. Thankfully your liver works hard for you, filtering, binding and eliminating these toxins. 

It always feels good to “give back” and there are so many things you can do to support your liver in this process. In addition to the things mentioned above, there is a supplement called calcium-d-glucarate which assists the liver in everyday detox.

Calcium-D-Glucarate can help decrease your cholesterol, assists in protein digestion, and helps remove toxins and excess estrogen. 

HOW YOUR BODY GETS RID OF TOXINS

One way your liver eliminates toxins is through a process called conjugation. During conjugation, toxins are packaged into water soluble compounds called glucuronides. Glucuronides are meant to pass through the liver, to the bile, then to the gut where they are excreted. Beta-glucuronidase is an enzyme that breaks the tight bond between glucuronides and toxins in the intestines. The binding of toxins in the gut is protective by way of blocking their absorption and facilitating excretion. Higher levels of beta-glucuronidase may be associated with an imbalanced intestinal microbiome, as well as higher circulating estrogens and decreased fecal excretion of estrogens. This allows toxins to continue to circulate in the body where they make you fat, tired, and weak.

HELLO CALCIUM-D-GLUCARATE

Calcium-D-Glucarate prevents high levels beta-glucuronidase from disturbing the detoxification process.  It keeps the toxins bound inside a “water soluble glucuronide package” which is then removed from the body.  Toxins are most damaging in their free form, which is why you want them to be bound (conjugated) and released from the body.  Calcium-D-Glucarate inhibits beta-glucuronidase and this allows the toxins to be removed more effectively.

There is technically not a deficiency of Calcium-D-Glucarate in the body because it is not essential. However, humans produce only small amounts, so it’s common to have low levels in your body.

Calcium-D-Glucarate is a natural substance your body produces. Small amounts are also found in fruits and vegetables. Years ago people were able to get enough Calcium-D-Glucarate from their own production since they ate relatively low amounts of toxins and lived in a clean environment. As toxin exposure increases, Calcium-D-Glucarate supplementation can assist in excreting the extra toxins.

FOUR BENEFITS OF TAKING A CALCIUM-D-GLUCARATE SUPPLEMENT

1. HELPS TO DETOX THE LIVER

Removing toxins from the liver will increase liver function and promote a healthy metabolism.  It will also allow your liver to flush out other toxins that would otherwise cause problems in your body..

2. HELPS TO REMOVE EXCESS ESTROGEN

High levels of beta-glucuronidase increases the number of estrogen receptors. This means estrogen that would have been excreted is now able to bind to more receptors. This can cause increased tissue growth and an inability to lose fat.

Estrogen dominance is one of the leading causes of infertility, mood imbalances, and other health problems in women.  

Calcium-D-Glucarate allows excess estrogen to be passed out of the body.  

High estrogen is also a problem for men.  Whether you are a man or woman, Calcium-D-Glucarate will help maintain proper hormone balance.

3. HELPS REDUCE CHOLESTEROL

Cholesterol is an important building block of hormones. Too much and too little cholesterol can cause problems in your body. As with many things in life, balance is the key.

Calcium-D-Glucarate is metabolized into glucaric salts.  Glucaric salts reduce beta-glucuronidase production by gut bacteria.  Reducing beta-glucuronidase enhances liver circulation which reduces cholesterol synthesis.  This causes lower cholesterol levels.

Calcium-D-Glucarate is not arbitrarily playing with cholesterol numbers, like the statin drugs.  It decreases stress on the liver which lowers your need for and production of cholesterol, especially LDL cholesterol.

When cells are stressed or damaged, they need cholesterol for repair. Inflammation in your body can be a root cause for high cholesterol levels. Decreasing inflammation through an anti-inflammatory diet, exercise and reducing stress can keep the need for cholesterol low, thus keeping cholesterol production in an optimal range.

4. ASSISTS IN ELIMINATION OF TOXIC BY-PRODUCTS OF PROTEIN METABOLISM

Your liver and kidneys are designed to efficiently process the protein you eat and allow for removal of harmful byproducts like ammonia.  However, with the excess toxic burden we experience today, your body is responsible not only for removing harmful byproducts like ammonia, but also for fending off xenoestrogens, air pollutants, chronic infections, and mycotoxins.  Consuming a high protein diet can definitely contribute to your body’s toxic burden. 

Suggested Protein Intake for an Average Adult:

  • 0.36 to 0.4 grams per pound body weight, 150 lbs = 54 to 60 grams/day
  • Protein should be in the 10 to 15% range of total calories
    • 1800 calories – 180 to 270 calories (45 to 68 grams)
    • 2000 calories – 200 to 300 calories (50 to 75 grams)
  • High Protein Diets (25-35%) can be detrimental to your health, consider decreasing your protein intake and supplementing with Calcium-D-Glucarate.

CALCIUM-D-GLUCARATE DOSAGE AND POSSIBLE INTERACTIONS

A normal detox dose is 500-1000 mg, 1 500mg capsule, once to twice daily. It can be taken with or without food.

If you have high estrogen levels, you may benefit from taking larger doses – ask your doctor before adding any supplement to your regimen.

Calcium-D-Glucarate can interact with alcohol and some drugs that act on the liver, like statins. WebMD has a full list of possible interactions.

You can purchase Calcium-D-Glucarate from Amazon or from your local health food store.

SUMMARY

Calcium-D-Glucarate can remove toxins, balance hormones, ensure healthy liver function, and lower cholesterol.


ALCOHOL’S EFFECT ON YOU AND YOUR LIVER

ALCOHOL IS PART OF OUR SOCIAL DYNAMIC

It can add an element of fun, silliness or sophistication to our experiences. However, it is helpful to be aware of the benefits and risks behind anything we choose to put into our body.

ALCOHOL CAN ADD HAPPINESS AND ENHANCE OUR EXPERIENCES

It is fun to have a cocktail with friends. It can help us relax and unwind. Spending time with friends and family is good for the spirit. Of course, it is possible to take things a little too far. Getting a little carried away and having a few too many might make your next morning a bit of a challenge, but how much harm can a few drinks really cause?

YOUR LIVER HAS MANY RESPONSIBILITES

The liver performs hundreds of functions, including metabolizing the fats, carbohydrates and proteins in our diet. The liver’s primary job is to filter toxins from the blood. Drinking alcohol gives your body extra work to do which keeps it from performing other jobs, like removing other harmful toxins and metabolizing your fats, carbohydrates and proteins.

ALCOHOL IS HIGH PRIORITY FOR YOUR LIVER

Once you have a drink containing alcohol, your body makes metabolizing it a priority because, unlike fats, carbohydrates and proteins, your body doesn’t have a way to store alcohol.

YOUR LIVER WORKS HARD TO GET IT ALL DONE

When you have a cocktail, beer or wine, your liver detoxifies and removes the alcohol thru a process called oxidation. The liver first converts the alcohol to another toxic substance called acetaldehyde. When oxidation is complete, acetaldehyde becomes water and carbon dioxide, which is excreted from the body.

A healthy liver can metabolize one alcoholic drink per hour. Have more than that, and the toxic acetaldehyde builds up in the body, causing a hangover. Drink too much too often, and the liver suffers damage.

FAT CONSEQUENCES OF TOO MUCH ALCOHOL

When you drink alcohol, the liver must choose to burn acetaldehyde for fuel instead of fat. If you drink too much too often, damage can result. Acetaldehyde damages the liver, and fat is stored in the liver instead of elsewhere in the body or being burned off altogether. This can lead to a condition called fatty liver disease. This is an early stage of liver disease and can typically be completely reversed in a month or two from simply abstaining from drinking alcohol and supporting your liver. Once liver damage has progressed beyond the fatty liver stage, damage typically becomes irreversible.

ALCOHOL’S EFFECT ON THE REST OF YOUR BODY

IMMUNE SYSTEM

Alcohol can weaken the immune system. If you drink every day, or almost every day, you may notice that you catch colds, flu or other illnesses more frequently than people who don’t drink.

DIGESTIVE SYSTEM

Drinking can upset the balance of the microorganisms in your digestive system. It can also damage the tissues in your GI tract and prevent you from digesting food and from absorbing nutrients and vitamins. Drinking alcohol can also lead to gassiness, bloating, and diarrhea.

CIRCULATORY SYSTEM

Alcohol can affect your heart and lungs. Chronic use of alcohol puts you at higher risk for heart related issues including: high blood pressure, irregular heartbeat, stroke, heart attack and heart disease.

SKELETAL AND MUSCLE SYSTEMS

Long-term alcohol use may prevent your body from keeping your bones strong. Thinner bones may increase your risk for fractures if you fall and these fractures may heal more slowly.

Drinking alcohol may also lead to muscle weakness and cramping.

CENTRAL NERVOUS SYSTEM

Slurred speech is one of the first signs you’ve had too much to drink. Alcohol can reduce communication between your body and your brain, impairing coordination.

THE GOOD NEWS: KNOWLEDGE IS POWER

Your liver is very resilient and capable of regenerating itself. It can develop new cells, but prolonged alcohol use over many years can reduce your liver’s ability to regenerate. Be kind to your body and support it in the best ways you can.

Empowered with this knowledge you can make your choices. “How much is too much?” is ultimately up to you.


DETOX STEP 2 – Liver Support

WHAT CAN YOU DO TO IMPROVE YOUR LIVER HEALTH?

Becoming aware of what is helpful and what is harmful is the first step. Taking actionable steps to implement these findings is the key to wellness.

YOUR DETOX SYSTEMS

  • Liver & Gallbladder
  • Gastrointestinal – Stomach, Intestines, Colon
  • Urinary – Kidneys, Bladder, Urethra
  • Skin – Sweat & Sebaceous Glands
  • Respiratory – Lungs, Throat, Sinuses, Mouth, Nose
  • Lymphatic – Channels & Nodes

CONDITIONS THAT MAY BE PRECIPITATED BY TOXINS

  • Anxiety
  • Depression
  • Cancer
  • Skin Rashes
  • Fatigue
  • Thyroid Issues
  • Prostate Issues
  • Fertility Issues
  • Auto Immune Conditions
  • Fibrocystic Breasts &/or Ovaries
  • Environmental Sensitivities
  • Constipation &/or Diarrhea
  • Bad Breath

THE LIVER – YOUR BODY’S FILTRATION SYSTEM

Think of your liver as being similar to a furnace filter. If not properly cared for, a furnace filter will get clogged. If you don’t provide a clean filter for the furnace it will not function efficiently and this could potentially cause damage to the furnace itself. The same is true of your liver. If detoxification is not supported and if you are taking in medications or other toxins that can impair the function of your liver, your body will not operate efficiently and could potentially be damaged.

  • Lack of detoxification supporting nutrition leads to malfunctioning systems in the body as toxins build up, this places an unwanted burden on the liver.
  • Good nutrition can prevent a lot of hardship, sickness and sadness
  • Your liver has two detoxification pathways: Phase I and II. These pathways are interrelated and both need to be supported for the liver to function efficiently.
  • The liver has many functions in the body: metabolizing the products of digestion from the stomach, processing and helping to rid the body of toxins, storing iron, providing essential energy producing substances, maintaining hormonal balance, regulating blood clotting, producing bile and producing cholesterol and other fats needed by the body.
  • If the liver malfunctions, toxins and hormones accumulate in the body causing inflammatory and neurological disease.
  • You can support your liver by limiting the toxic load you are taking in from your environment and by supporting its function through your dietary intake of nourishing organic nutrients, antioxidants and phytochemicals.
  • Evaluate your cleaning supplies, cosmetics, lotions, tampons, plastics, soaps, detergents, and new carpet, flooring & furniture (off-gassing).
  • Compounds in the following foods have been found to support the liver detox process:
    • Cruciferous Vegetables
    • Green Leafy Vegetables
    • Garlic
    • Onion
    • Cardamom
    • Turmeric
  • There are many things that can inhibit your liver’s function
    • Medications
      • Antihistamines (Claritin, Zyrtec, Benadryl, Allegra)
      • Benzodiazepines (Valium, Xanax)
      • H2 Blockers (Tagamet, Zantac)
      • Antifungals
      • Antibiotics
    • Deficiencies in Vitamins & Minerals
      • Vitamin B2
      • Vitamin B3
      • Copper
      • Magnesium
      • Zinc
    • Grapefruit Juice
    • Age, decreased blood flow to the liver
    • Lack of Physical Activity
    • Poor Nutrition

IMPORTANT: Support and Balance Both Phases of Liver Detoxification. If Phase II is slower than Phase I, then the toxins processed by Phase I are in a state that can cause more harm in the body. This imbalance can occur in two ways: over burdening the Phase I process and under nourishing the Phase II process.

PHASE I (TRANSFORMATION) – Start the Job: Lessen the Burden Phase I of liver detox is burdened by the over exposure to environmental toxins: from the air we breathe, the water we drink, the contaminants and pesticides in the food we eat, and all other toxins we introduce through topical products, cleaning supplies and medications, both over-the-counter and prescription. All of these add to the burden on the liver. This excessive burden can impair the liver’s ability to properly metabolize the toxins and the liver will produce a dangerously high level of free radicals that must be further metabolized by Phase II to protect against oxidative cell damage.

Phase II (CONJUGATION) – Finish the Job: Bind the Toxins Phase II of liver detoxification has a huge job to conjugate and eliminate the bio-transformed substances from Phase I. If the Phase II process is impaired, due to a lack of micronutrients, antioxidants and phytochemicals, it is not capable of keeping up with the toxic load it is given from the Phase I process. These substances are potentially more toxic now that they have been transformed. If the water soluble toxic substances are not effectively eliminated from the body, they are now more dangerous because they can attach to cells in the body other than fat cells, where they are typically stored.

LIVER DETOXIFICATION IS ESSENTIAL FOR HEALTH If the liver malfunctions, toxins and hormones accumulate in the body causing inflammatory and neurological disease.

Supporting your liver function is just one great reason to eat organic and to incorporate juice fasting into your dietary plan.

HERE’S WHAT YOU CAN DO:

  • Limit toxins taken into or put onto your body
  • Support your liver with organic vegetables, garlic, onion, cardamom & turmeric
  • Incorporate juice fasting into your dietary plan.

It may not be realistic for you to eat 100% organic or to completely eliminate all environmental toxins but your health is definitely worth making the effort.