WHY CALCIUM-D-GLUCARATE?

A SUPPLEMENT TO SUPPPORT DETOXIFICATION

YOUR BODY IS AMAZING

Your body is amazing! It is always working behind the scenes to support you. 

Do you remember Benjamin Franklin’s old saying: “An ounce of prevention is worth a pound of cure?” Your prevention is supporting your body with self care, sleep, being in nature, exercise and of course organic, unrefined, unprocessed foods, as fresh as possible and in their natural state. This is the best way to prevent overburdening your body with unwanted toxins.

Toxins will still find a way into your body: through the air you breathe, water you drink, foods you eat, items you clean with and products you put on your skin. Thankfully your liver works hard for you, filtering, binding and eliminating these toxins. 

It always feels good to “give back” and there are so many things you can do to support your liver in this process. In addition to the things mentioned above, there is a supplement called calcium-d-glucarate which assists the liver in everyday detox.

Calcium-D-Glucarate can help decrease your cholesterol, assists in protein digestion, and helps remove toxins and excess estrogen. 

HOW YOUR BODY GETS RID OF TOXINS

One way your liver eliminates toxins is through a process called conjugation. During conjugation, toxins are packaged into water soluble compounds called glucuronides. Glucuronides are meant to pass through the liver, to the bile, then to the gut where they are excreted. Beta-glucuronidase is an enzyme that breaks the tight bond between glucuronides and toxins in the intestines. The binding of toxins in the gut is protective by way of blocking their absorption and facilitating excretion. Higher levels of beta-glucuronidase may be associated with an imbalanced intestinal microbiome, as well as higher circulating estrogens and decreased fecal excretion of estrogens. This allows toxins to continue to circulate in the body where they make you fat, tired, and weak.

HELLO CALCIUM-D-GLUCARATE

Calcium-D-Glucarate prevents high levels beta-glucuronidase from disturbing the detoxification process.  It keeps the toxins bound inside a “water soluble glucuronide package” which is then removed from the body.  Toxins are most damaging in their free form, which is why you want them to be bound (conjugated) and released from the body.  Calcium-D-Glucarate inhibits beta-glucuronidase and this allows the toxins to be removed more effectively.

There is technically not a deficiency of Calcium-D-Glucarate in the body because it is not essential. However, humans produce only small amounts, so it’s common to have low levels in your body.

Calcium-D-Glucarate is a natural substance your body produces. Small amounts are also found in fruits and vegetables. Years ago people were able to get enough Calcium-D-Glucarate from their own production since they ate relatively low amounts of toxins and lived in a clean environment. As toxin exposure increases, Calcium-D-Glucarate supplementation can assist in excreting the extra toxins.

FOUR BENEFITS OF TAKING A CALCIUM-D-GLUCARATE SUPPLEMENT

1. HELPS TO DETOX THE LIVER

Removing toxins from the liver will increase liver function and promote a healthy metabolism.  It will also allow your liver to flush out other toxins that would otherwise cause problems in your body..

2. HELPS TO REMOVE EXCESS ESTROGEN

High levels of beta-glucuronidase increases the number of estrogen receptors. This means estrogen that would have been excreted is now able to bind to more receptors. This can cause increased tissue growth and an inability to lose fat.

Estrogen dominance is one of the leading causes of infertility, mood imbalances, and other health problems in women.  

Calcium-D-Glucarate allows excess estrogen to be passed out of the body.  

High estrogen is also a problem for men.  Whether you are a man or woman, Calcium-D-Glucarate will help maintain proper hormone balance.

3. HELPS REDUCE CHOLESTEROL

Cholesterol is an important building block of hormones. Too much and too little cholesterol can cause problems in your body. As with many things in life, balance is the key.

Calcium-D-Glucarate is metabolized into glucaric salts.  Glucaric salts reduce beta-glucuronidase production by gut bacteria.  Reducing beta-glucuronidase enhances liver circulation which reduces cholesterol synthesis.  This causes lower cholesterol levels.

Calcium-D-Glucarate is not arbitrarily playing with cholesterol numbers, like the statin drugs.  It decreases stress on the liver which lowers your need for and production of cholesterol, especially LDL cholesterol.

When cells are stressed or damaged, they need cholesterol for repair. Inflammation in your body can be a root cause for high cholesterol levels. Decreasing inflammation through an anti-inflammatory diet, exercise and reducing stress can keep the need for cholesterol low, thus keeping cholesterol production in an optimal range.

4. ASSISTS IN ELIMINATION OF TOXIC BY-PRODUCTS OF PROTEIN METABOLISM

Your liver and kidneys are designed to efficiently process the protein you eat and allow for removal of harmful byproducts like ammonia.  However, with the excess toxic burden we experience today, your body is responsible not only for removing harmful byproducts like ammonia, but also for fending off xenoestrogens, air pollutants, chronic infections, and mycotoxins.  Consuming a high protein diet can definitely contribute to your body’s toxic burden. 

Suggested Protein Intake for an Average Adult:

  • 0.36 to 0.4 grams per pound body weight, 150 lbs = 54 to 60 grams/day
  • Protein should be in the 10 to 15% range of total calories
    • 1800 calories – 180 to 270 calories (45 to 68 grams)
    • 2000 calories – 200 to 300 calories (50 to 75 grams)
  • High Protein Diets (25-35%) can be detrimental to your health, consider decreasing your protein intake and supplementing with Calcium-D-Glucarate.

CALCIUM-D-GLUCARATE DOSAGE AND POSSIBLE INTERACTIONS

A normal detox dose is 500-1000 mg, 1 500mg capsule, once to twice daily. It can be taken with or without food.

If you have high estrogen levels, you may benefit from taking larger doses – ask your doctor before adding any supplement to your regimen.

Calcium-D-Glucarate can interact with alcohol and some drugs that act on the liver, like statins. WebMD has a full list of possible interactions.

You can purchase Calcium-D-Glucarate from Amazon or from your local health food store.

SUMMARY

Calcium-D-Glucarate can remove toxins, balance hormones, ensure healthy liver function, and lower cholesterol.


DETOX STEP 2 – Liver Support

WHAT CAN YOU DO TO IMPROVE YOUR LIVER HEALTH?

Becoming aware of what is helpful and what is harmful is the first step. Taking actionable steps to implement these findings is the key to wellness.

YOUR DETOX SYSTEMS

  • Liver & Gallbladder
  • Gastrointestinal – Stomach, Intestines, Colon
  • Urinary – Kidneys, Bladder, Urethra
  • Skin – Sweat & Sebaceous Glands
  • Respiratory – Lungs, Throat, Sinuses, Mouth, Nose
  • Lymphatic – Channels & Nodes

CONDITIONS THAT MAY BE PRECIPITATED BY TOXINS

  • Anxiety
  • Depression
  • Cancer
  • Skin Rashes
  • Fatigue
  • Thyroid Issues
  • Prostate Issues
  • Fertility Issues
  • Auto Immune Conditions
  • Fibrocystic Breasts &/or Ovaries
  • Environmental Sensitivities
  • Constipation &/or Diarrhea
  • Bad Breath

THE LIVER – YOUR BODY’S FILTRATION SYSTEM

Think of your liver as being similar to a furnace filter. If not properly cared for, a furnace filter will get clogged. If you don’t provide a clean filter for the furnace it will not function efficiently and this could potentially cause damage to the furnace itself. The same is true of your liver. If detoxification is not supported and if you are taking in medications or other toxins that can impair the function of your liver, your body will not operate efficiently and could potentially be damaged.

  • Lack of detoxification supporting nutrition leads to malfunctioning systems in the body as toxins build up, this places an unwanted burden on the liver.
  • Good nutrition can prevent a lot of hardship, sickness and sadness
  • Your liver has two detoxification pathways: Phase I and II. These pathways are interrelated and both need to be supported for the liver to function efficiently.
  • The liver has many functions in the body: metabolizing the products of digestion from the stomach, processing and helping to rid the body of toxins, storing iron, providing essential energy producing substances, maintaining hormonal balance, regulating blood clotting, producing bile and producing cholesterol and other fats needed by the body.
  • If the liver malfunctions, toxins and hormones accumulate in the body causing inflammatory and neurological disease.
  • You can support your liver by limiting the toxic load you are taking in from your environment and by supporting its function through your dietary intake of nourishing organic nutrients, antioxidants and phytochemicals.
  • Evaluate your cleaning supplies, cosmetics, lotions, tampons, plastics, soaps, detergents, and new carpet, flooring & furniture (off-gassing).
  • Compounds in the following foods have been found to support the liver detox process:
    • Cruciferous Vegetables
    • Green Leafy Vegetables
    • Garlic
    • Onion
    • Cardamom
    • Turmeric
  • There are many things that can inhibit your liver’s function
    • Medications
      • Antihistamines (Claritin, Zyrtec, Benadryl, Allegra)
      • Benzodiazepines (Valium, Xanax)
      • H2 Blockers (Tagamet, Zantac)
      • Antifungals
      • Antibiotics
    • Deficiencies in Vitamins & Minerals
      • Vitamin B2
      • Vitamin B3
      • Copper
      • Magnesium
      • Zinc
    • Grapefruit Juice
    • Age, decreased blood flow to the liver
    • Lack of Physical Activity
    • Poor Nutrition

IMPORTANT: Support and Balance Both Phases of Liver Detoxification. If Phase II is slower than Phase I, then the toxins processed by Phase I are in a state that can cause more harm in the body. This imbalance can occur in two ways: over burdening the Phase I process and under nourishing the Phase II process.

PHASE I (TRANSFORMATION) – Start the Job: Lessen the Burden Phase I of liver detox is burdened by the over exposure to environmental toxins: from the air we breathe, the water we drink, the contaminants and pesticides in the food we eat, and all other toxins we introduce through topical products, cleaning supplies and medications, both over-the-counter and prescription. All of these add to the burden on the liver. This excessive burden can impair the liver’s ability to properly metabolize the toxins and the liver will produce a dangerously high level of free radicals that must be further metabolized by Phase II to protect against oxidative cell damage.

Phase II (CONJUGATION) – Finish the Job: Bind the Toxins Phase II of liver detoxification has a huge job to conjugate and eliminate the bio-transformed substances from Phase I. If the Phase II process is impaired, due to a lack of micronutrients, antioxidants and phytochemicals, it is not capable of keeping up with the toxic load it is given from the Phase I process. These substances are potentially more toxic now that they have been transformed. If the water soluble toxic substances are not effectively eliminated from the body, they are now more dangerous because they can attach to cells in the body other than fat cells, where they are typically stored.

LIVER DETOXIFICATION IS ESSENTIAL FOR HEALTH If the liver malfunctions, toxins and hormones accumulate in the body causing inflammatory and neurological disease.

Supporting your liver function is just one great reason to eat organic and to incorporate juice fasting into your dietary plan.

HERE’S WHAT YOU CAN DO:

  • Limit toxins taken into or put onto your body
  • Support your liver with organic vegetables, garlic, onion, cardamom & turmeric
  • Incorporate juice fasting into your dietary plan.

It may not be realistic for you to eat 100% organic or to completely eliminate all environmental toxins but your health is definitely worth making the effort.


DETOX STEP 1 – Am I healthy?

I was joking with a patient the other day, when asked about health and nutrition. She was asking for advice but maintaining that she always eats healthy. It came to me in a flash that we all believe that we eat healthy. Why would we purposely do anything to harm our body? I shared with her, that so did I, ever since I can remember having the freedom to choose my own food in 7th grade.

My “healthy” diet was Diet Coke for breakfast and a slice of pizza at the local pizza place for lunch. Of course, I had a mom who packed me a lunch everyday (THANKFULLY!!) that contained fruits and vegetables. But when left to my own choosing it was Diet Coke and Pizza. I lost almost 20 pounds from 6th Grade to 8th Grade. Retrospectively, I was going thru puberty and my hormones and my growth shed the extra pounds naturally, as it often does for teenage girls; but I attributed this to my new “healthy” diet.

This continued into High School where pizza was exchanged for McDonald’s or Hardee’s and still the Diet Coke remained a staple. No one was teaching us about nutrition; well, except for the one week unit in health class that reminded us to eat mostly grains and to add some fruits and vegetables for good measure. This is where I added in Ramen noodles with canned peas or corn for a “well rounded” meal.

Once I graduated and went off to college, I really had a handle on healthy eating. I followed the latest food “guidelines”. Any of you who experienced the 90’s as a young adult know what I am talking about: avoid fat at all costs, eat carbs, eat less and exercise more. I thankfully still enjoyed fruits and vegetables because this is what I was raised on (when my mom was in charged of feeding me). I followed this to the letter: pasta, canned corn, canned beans, meat of any kind on occasion (when I felt the need) and don’t forget the Snack Well Cookies – no fat and only 100 calories. Diet Coke still prevailed and now that I was “grown up”, add a splash of booze when needed! I ran and worked out all the time!! By my last year in school, I was down to an “acceptable” weight, after gaining the obligatory 15 pounds at the beginning of college. Again, thanks to my “healthy” lifestyle.

Out into the real world I went! A job, an apartment, a car, a new stereo and money I hadn’t had in college. Now I could go out for breakfast, lunch and dinner. This started to catch up to me and I naturally migrated back to cooking and adding in more whole food (thankfully) but still unconsciously.

It wasn’t until I was planning to get pregnant with my first child that I really started researching healthy eating. Not for me necessarily, but to give my baby the best start possible in life. I quit coffee cold turkey (what a miserable couple of weeks of headaches and nausea), I gave up Diet Coke and switched to the occasional “Real” Coke. I added more fruits and vegetables at every meal and started taking a multivitamin. This is were my journey really started, with my concern for the health of my daughters at the forefront and eventually for my own health.

Again, in retrospect, I am amazed that I emerged from that experience unaffected, or so I thought! It was just a few extra pounds, a little fatigue, and sprinkled with a bit (or a lot) of postpartum depression.

Then, over time, the real effects started to show up. The fatigue got worse; I didn’t have the energy to exercise so the weight remained a bit elevated. Then the sluggish thyroid turned into Hashimoto’s and finally the rheumatoid arthritis was revealed!!

I no longer focus on why this happened, other than to move me toward a healthier place. There is a whole world of epigenetics to explore. In a nutshell, this is looking at what external factors trigger modification of your gene expression. I just began to focus on what external factors I could control to modify this again.

The point of this story is that we need to reflect on what we believe to be healthy and what we could do to improve upon this. We are only able to welcome change if we first change our mindset. Once we allow this paradigm shift, change will begin.

The good news is that our bodies are amazingly designed to detoxify and excrete toxins.

“Take care of your body. It's the only place you have to live.” 
― Jim Rohn. 

The bad news is that our bodies are not equipped to handle the sheer volume of modern environmental and other toxins we are exposed to today; and some of us are less equipped than others.

We have so many toxin exposures every single day!

COMMON TOXINS: Food toxins, air pollutants, water pollutants: pesticide residue, pharmaceuticals residue, hormone disruptors, nitrates from fertilizers, heavy metals (mercury from fish), GMOs from factory farmed animals, PCBs, dioxin from paper products and tampons, pesticides on non-organic produce, cleaning supplies, cosmetics and grooming products, plastics, detergents and soaps, carpet.

We should incorporate detox regularly, not just ONE AND DONE.

I have started looking at it like cleaning my house. I like to keep up on the mess and the laundry to prevent it from building up, but every month or two I need to do a cleanse and clean up and clear out the things that are cluttering up and interfering with my space. Sometimes this gets away from me and it will be 6 months or a year before I address some of these things. This is a direct parallel to our bodies. We will do ourselves a wonderful service by cleaning up our diet and eliminating as many toxins as possible, but we still need to neutralize and clear out the toxins that have gotten in.

Questions to Ponder:

  • Where am I at today?
  • What can I do right now?
  • Will I allow myself to be paralyzed by fear?
  • Will I allow this to empower me to seek solutions?

Where do I start?

  • Food is always a good place to start
  • Choosing organic when possible and especially when necessary
  • The EWG (Environmental Working Group) is a fantastic group that makes this process a little easier!
  • The Clean Fifteen & The Dirty Dozen